Liverpool continued their poor run of form with an FA Cup defeat at Manchester United on Sunday.
Two goals from Mohamed Salah weren’t enough as the Reds were dumped out of the competition after a 3-2 fourth round reverse.
The Premier League and world champions now have a quick turnaround before they head to Tottenham Hotspur on Thursday.
And here we look ahead to the changes Jurgen Klopp could make when his team are next in action.
The defensive question
Liverpool were stronger in defence than many had anticipated at Old Trafford.
Alisson Becker will surely continue between the sticks, while left-back Andy Robertson was one of the better performers at the weekend.
Trent Alexander-Arnold was improved on his showing against Burnley having been preferred to Neco Williams at right-back.
Centre-back, though, is where matters could become interesting.
Joel Matip is likely to be back having been rested at United, although it may not be guaranteed that Fabinho remains as his central defensive partner.
While Rhys Williams had a difficult time on Sunday, Nat Phillips has been waiting patiently for an opportunity while Jordan Henderson, if fit, is another option.
The engine room was overhauled against United and, as a consequence, has offered Klopp an opportunity for a rethink.
Curtis Jones did well when switched into a central role, while James Milner performed admirably but may not be up to two games inside a week.
With options available, there is the possibility of pushing Fabinho into midfield although the recall of Henderson is more likely should the skipper be available.
Gini Wijnaldum and Thiago Alcantara have been mainstays in recent weeks but neither was on top form on Sunday.
Alex Oxlade-Chamberlain is another alternative, while Liverpool are still waiting on Naby Keita to return.
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Forward trio reunited
With Tottenham similarly scrapping it out for a top-four berth, Thursday’s match will have serious ramifications in the race for Champions League qualification.
Salah and Roberto Firmino were recalled at United and, having combined for the two goals, are almost certain to start in London.
Sadio Mane will be primed to join them having been benched at the weekend, with Jones having been preferred down the left.
Xherdan Shaqiri and Divock Origi are likely to be restricted to substitute roles, while Takumi Minamino has slipped a little further out of contention for a starting role.