Here some of the first people in Wales to receive Pfizer’s Covid-19 jab as part of a mass vaccination programme.
Jabs will be administered at 70 hospital hubs across the UK from Tuesday – dubbed ‘V-Day’ with vaccinations being carried out in all of Wales’ health boards.
Frontline health workers David Farrell, 51, from Llandow, and Lara Jesani, 26, from Cardiff, were among the first at a vaccination centre in Cardiff.
Some 40 million doses of the Pfizer-BioNTech vaccine will be available across the UK, with Wales getting its allocation based on its population. In the first wave of vaccine deliveries, Wales will receive almost 40,000 doses, enough for nearly 20,000 people.
All Welsh health boards will start administering vaccines to care home staff, those over 80 years and frontline health and social care workers most at risk – over 6,000 doses will be given by the end of this week.
The vaccine has been shown to be 95% effective against Covid-19 and works across all age groups, including the elderly.
Earlier, 90-year-old grandmother Margaret Keenan became the first person in the world to have the vaccine when she was given the jab at 6.31am in Coventry on Tuesday.
Mrs Keenan, known to family and friends as Maggie, received the jab from nurse May Parsons at University Hospital in Coventry.
Mrs Keenan, who turns 91 next week, is a former jewellery shop assistant who retired four years ago.
She has a daughter, a son and four grandchildren.
Mrs Keenan said: “I feel so privileged to be the first person vaccinated against Covid-19. It’s the best early birthday present I could wish for because it means I can finally look forward to spending time with my family and friends in the new year after being on my own for most of the year.
“I can’t thank May and the NHS staff enough who have looked after me tremendously, and my advice to anyone offered the vaccine is to take it – if I can have it at 90 then you can have it too.
“I don’t mind the attention, it doesn’t bother me. I’m just happy to have it done.
“This is a terrible disease so we do want rid of it, so anything that helps is a bonus, isn’t it?”
First Minister Mark Drakeford said: “Last week, Wales was the first country in the world to receive supplies of the Covid-19 vaccine. Today, I’m very proud Wales has become one of the first countries in the world to begin the roll-out of the vaccine to its population.
“2020 has been a very difficult year for all of us. This vaccine is a small glimmer of light at the end of what has been a long and dark tunnel.
“But the fact we have a vaccine does not mean we can stop doing those things that keep us safe. We must all continue to do our bit to prevent the spread of coronavirus: regular hand washing, social distancing, and wearing a face covering where required to protect yourself and others.”
Prime Minister Boris Johnson praised everyone involved in the vaccine’s development, tweeting: “Thank you to our NHS, to all of the scientists who worked so hard to develop this vaccine, to all the volunteers – and to everyone who has been following the rules to protect others. We will beat this together.”
The UK is the first country in the world to start using the Pfizer vaccine after regulators approved its use last week.
Mrs Keenan has been self-isolating for most of this year and is planning on having a very small family “bubble” Christmas to keep safe.
Originally from Enniskillen, Northern Ireland, she has lived in Coventry for more than 60 years.
She will receive a booster jab in 21 days to ensure she has the best chance of being protected against the virus.
NHS nurse Mrs Parsons said it was a “huge honour” to be the first in the country to deliver the vaccine to a patient.
She said: “It’s a huge honour to be the first person in the country to deliver a Covid-19 jab to a patient, I’m just glad that I’m able to play a part in this historic day.
“The last few months have been tough for all of us working in the NHS, but now it feels like there is light at the end of the tunnel.”
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Scotland’s First Minister Nicola Sturgeon tweeted: “Got a bit of a lump in the throat watching this. Feels like such a milestone moment after a tough year for everyone.”
The NHS Covid-19 vaccination programme will see patients aged 80 and above who are already attending hospital as an outpatient, and those who are being discharged home after a hospital stay, among the first to receive the jab.