With Arsenal already through to the last 32, Mikel Arteta makes 11 changes to the side that lost at home to Wolves on Sunday. Most of those 11 players are on the bench, though David Luiz and Pierre-Emerick Aubameyang are among those given the night off.
Arsenal (4-2-3-1) Runarsson; Cedric, Mustafi, Pablo Mari, Kolasinac; Maitland-Niles, Elneny; Pepe, Lacazette, Nelson; Nketiah.
Substitutes Leno, Macey, Tierney, Saka, Ceballos, Willian, Holding, Chambers, Willock, Smith Rowe, Balogun, Azeez.
Rapid Vienna (3-5-2) Strebinger; Sonnleitner, M Hofmann, Greiml; Arase, Demir, Schuster, Ritzmaier, Ullmann; Kitagawa, Alar.
Substitutes Gartler, Hedl, Barac, Schick, Grahovac, Stojkovic, Knasmullner, Kara, Sulzbacher, Melih Ibrahimoglu.